Protein Name & Synonyms:
ELOA, SIII, SIII p110, TCEB3, TCEB3A, SIIIp110, elongin-A
WB, IHC, IF
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Human, Mouse, Rat
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200
Recombinant fusion protein containing a sequence corresponding to amino acids 679-798 of human TCEB3 (NP_003189.2).
Store at -20°. Avoid freeze / thaw cycles.
12 months from the date of shipment when stored properly.