Rabbit anti-TCEB3 Antibody

TCEB3 pAb

$416.00  
144-66263-200
+

Protein Information

Accession Number:
  • Q14241
Gene ID:
  • 6924
Gene Symbols:
  • TCEB3
Protein Name & Synonyms:
ELOA, SIII, SIII p110, TCEB3, TCEB3A, SIIIp110, elongin-A
Target Species:
  • Human

Antibody Specifications

Applications:
WB, IHC, IF
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human, Mouse, Rat
Isotype:
IgG

Background

This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.

Dilutions

WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200

Format

Calculated MW
89kDa
Observed MW
105kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 679-798 of human TCEB3 (NP_003189.2).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:
12 months from the date of shipment when stored properly.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.

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