Protein Name & Synonyms:
Western Blot analysis (0.5-4 ug/ml). It detects 64 kDa TCTN1 and its cleavage fragment. However, the optimal concentrations should be determined individually. Blocking peptide is available separately.
TCTN1 belongs to the Tectonic protein family that regulate Hedgehog (Hh) pathway. During neural tube development, TCTN1 is required for the formation of most ventral cell types and for full Hh pathway activation. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
Synthetic peptide surrounding amino acid 520 of rat TCTN1
100 µg (0.5 mg/ml) affinity purified rabbit anti- TCTN1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Jurkat cell lysate
-20 °C. The shelf life is 12 months.