Rabbit Anti-TGF-beta2 Antibody

Rabbit Anti-TGF-beta2 Antibody, (100 ug)

$355.00
168-10915
+

Antigen Information

Accession Number:
  • BAG35929
Protein Name & Synonyms:
TGF-beta2

Antibody Specifications

Applications:
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually.
Concentration:
0.5 mg/ml
Host Species:
Rabbit

Synonyms

TGF-b2, TGF b2 TGF-beta2, TGF beta-2, TGFbeta, TGFb2, transforming growth factor beta 2

Description

The three mammalian isoforms of TGF-beta (TGF-beta1, TGF-beta2, TGF-beta3) signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and would healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-beta isoform from a latent complex involves proteolytic processing of the complex and/or induction of conformational changes by proteins such as thrombospondin-1. TGF-beta2 has been shown to exert suppressive effects on IL-2 dependent T-cell growth, and may also have an autocrine function in enhancing tumor growth by suppressing immuno-surveillance of tumor development.

Source

Immunogen
E. coli expressed recombinant human TGF-❏2
Purification
Affinity purified

Format

Physical Appearance
Colorless liquid
Formulation
100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Specificity

TGF-b2

Storage

-20 °C. The shelf life is 12 months.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.