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Rabbit anti-TIMP1 Antibody

TIMP1 pAb

$200.00  
144-62970-50
+

Antigen Information

Accession Number:
  • P01033
Gene ID:
  • 7076
Gene Symbols:
  • TIMP1
Protein Name & Synonyms:
TIMP1, CLGI, EPA, EPO, HCI, TIMP, TIMP-1, metalloproteinase inhibitor 1
Target Species:
  • Human

Antibody Specifications

Applications:
WB, IF
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human, Mouse
Isotype:
IgG

Background

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Dilutions

WB 1:500 - 1:2000; IF 1:50 - 1:200

Format

Calculated MW
23kDa
Observed MW
28kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 24-207 of human TIMP1 (NP_003245.1).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.