Protein Name & Synonyms:
TMX1, PDIA11, TMX, TXNDC, TXNDC1, thioredoxin-related transmembrane protein 1
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides.
WB 1:500 - 1:2000
Recombinant fusion protein containing a sequence corresponding to amino acids 210-280 of human TMX1 (NP_110382.3).
Immunohistochemistry of paraffin-embedded rat brain using TMX1 antibody (144-60854) at dilution of 1:100 (40x lens).