Protein Name & Synonyms:
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~47 kDa Trek 1 of human, mouse, and rat origins. Reactivity to other species has not been tested.
K2p2.1; KCNK2; MGC126742; MGC126744; TPKC1; TREK; TREK-1; TREK1; hTREK-1c; hTREK-1e
Trek-1 and Trek-2 belong to the tandem-pore K+ channel family that has two pore-forming domains and four transmembrane segments. Trek-1 is expressed throughout the central nervous system whereas Trek-2 is found mostly in the cerebellum, spleen and testis. Trek-1 is activated by arachidonic acid and polyunsaturated fatty acids.
Synthetic peptide corresponding to residues surrounding amino acids 417 of mouse Trek-1
100 µg (0.5 mg/ml) affinity purified rabbit anti-Trek-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
-20 °C. The shelf life is 12 months.