NEW

Rabbit anti-UMPS Antibody

UMPS pAb

$200.00  
144-62715-50
+

Antigen Information

Accession Number:
  • P11172
Gene ID:
  • 7372
Gene Symbols:
  • UMPS
Protein Name & Synonyms:
UMPS, OPRT, uridine monophosphate synthetase
Target Species:
  • Human

Antibody Specifications

Applications:
WB, IF
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human, Mouse, Rat
Isotype:
IgG

Background

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Dilutions

WB 1:500 - 1:2000; IF 1:50 - 1:100

Format

Calculated MW
22kDa/33kDa/42kDa/52kDa
Observed MW
57kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human UMPS (NP_000364.1).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

No posts found

Write A Review

Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.