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Antigen Information
Protein Name & Synonyms:
CD18
Target Species:
- Human
Antibody Specifications
Applications:
Flow Cytometry
Reconstitution:
Reconstitute with 1 ml distilled water
Species Reactivity:
Human, This antibody is reported to cross react with canine
Specificity
This product was clustered at the Fourth International Workshop on Leukocyte Differentiation Antigen (code number N221) as recognising the CD18 antigen.
The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight - known as the b chain, of the LFA-1 complex. The CD18 antigen is non-covalently linked to CD11a, b, c molecules.
The main cellular reactivity of this antibody is a strong reactivity with leukocytes (platelets negative).
The CD18 molecule is the receptor for ICAM-1 and is thus important for cell adhesion. This antibody blocks homotypic adhesion and other lymphocyte functions which involve the LFA-1 antigen.
The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight - known as the b chain, of the LFA-1 complex. The CD18 antigen is non-covalently linked to CD11a, b, c molecules.
The main cellular reactivity of this antibody is a strong reactivity with leukocytes (platelets negative).
The CD18 molecule is the receptor for ICAM-1 and is thus important for cell adhesion. This antibody blocks homotypic adhesion and other lymphocyte functions which involve the LFA-1 antigen.
Storage/Stability
Prior to reconstitution store at +4 °C. Following reconstitution store at +4 °C.
DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute with 1 ml distilled water
Preparation
Immunogen:
Human neutrophils
Preservative:
| 0.09% | Sodium Azide |
| 1% | Bovine Serum Albumin |
| 5% | Sucrose |
This product
Spleen cells from immunised LOU rats were fused with cells of the Y3/Ag.1.2.3 rat myeloma cell line.
No posts found
Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
