Protein Name & Synonyms:
EGFR / ErbB1
Applications:
Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation, Immunohistology - Paraffin
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human
This product recognizes the human epidermal growth factor receptor (EGF-R), which is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas.
High level expression of EGFR is often associated with advanced disease and poor prognosis.
This product binds to epitope B from EGFR (1, 2) and has an affinity of 6.7 x 10-9 M.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Immunogen:
Extracellular domain of human EGF-receptor from head and neck carcinoma