Protein Name & Synonyms:
HLA DR
Applications:
Flow Cytometry
Reconstitution:
Reconstitute with 1.0 ml distilled water
Species Reactivity:
Human
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class II proteins encoded by the HLA which are HLA DP, HLA DQ and HLA DR.
This product recognizes a monomorphic determinant of human HLA DR which is an MHC class II cell surface receptor expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages and activated T lymphocytes.
This product has also been reported to be cross reactive with mouse H-2 haplotypes b, d and q expressed by mouse strains including C57BL/6, DBA, and NZB, see Brickell, P.M. et al. for details.
Prior to reconstitution store at +4 °C. Following reconstitution store at +4 °C.
This product should be stored undiluted.
DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.
Supplied as:
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute with 1.0 ml distilled water
Immunogen:
EHR-B Ramos cells
Preservative:
0.09% | Sodium Azide |
1% | Bovine Serum Albumin |
5% | Sucrose |
This product
Spleen cells from immunised AO rats were fused with cells of the rat Y3 Ag1.2.3 myeloma cell line.
Expiration:
12 months from the date of shipment when stored properly.