Rat Anti-Human HLA DR [+RPE]

Rat Anti-Human HLA DR [+RPE]

DS-MB-03676
+

Antigen Information

Protein Name & Synonyms:
HLA DR
Target Species:
  • Human

Antibody Specifications

Applications:
Flow Cytometry
Reconstitution:
Reconstitute with 1.0 ml distilled water
Species Reactivity:
Human

Specificity

The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class II proteins encoded by the HLA which are HLA DP, HLA DQ and HLA DR.

This product recognizes a monomorphic determinant of human HLA DR which is an MHC class II cell surface receptor expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages and activated T lymphocytes.

This product has also been reported to be cross reactive with mouse H-2 haplotypes b, d and q expressed by mouse strains including C57BL/6, DBA, and NZB, see Brickell, P.M. et al. for details.

Storage/Stability

Prior to reconstitution store at +4 °C. Following reconstitution store at +4 °C.

This product should be stored undiluted.

DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.

Format

Supplied as:
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute with 1.0 ml distilled water

Preparation

Immunogen:
EHR-B Ramos cells
Preservative:
0.09%Sodium Azide
1%Bovine Serum Albumin
5%Sucrose
This product
Spleen cells from immunised AO rats were fused with cells of the rat Y3 Ag1.2.3 myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.