Rat Anti-Mouse beta-Glucan Receptor

Rat Anti-Mouse beta-Glucan Receptor


Antigen Information

Protein Name & Synonyms:
beta-Glucan Receptor
Target Species:
  • Mouse

Antibody Specifications

Immunohistology - Frozen, Flow Cytometry, Functional Assays, Immunoprecipitation
IgG concentration 1.0 mg/ml
Species Reactivity:


This product recognizes murine beta-glucan receptor, also known as Dectin-1.Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells.

As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens.

Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk.


Store at -20 °C only.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.


Supplied as:
Purified IgG - liquid
Phosphate buffered saline
Quality Control (Contaminants):
<0.01 EU/ug
Format Type:
Low Endotoxin


Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1
None present
This product
Spleen cells from immunised Fischer rats were fused with cells of the rat Y3 myeloma cell line

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This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.