Rat Anti-Mouse beta-Glucan Receptor [+FITC]

Rat Anti-Mouse beta-Glucan Receptor [+FITC]

DS-MB-03702
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Antigen Information

Protein Name & Synonyms:
beta-Glucan Receptor
Target Species:
  • Mouse

Antibody Specifications

Applications:
Flow Cytometry
Concentration:
IgG concentration 0.5 mg/ml
Species Reactivity:
Mouse

Specificity

This product recognizes murine beta-glucan receptor, also known as Dectin-1.Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells.

As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens.

Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.

Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline

Preparation

Immunogen:
Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1
Preservative:
0.09%Sodium Azide
1%Bovine Serum Albumin
This product
Spleen cells from immunised Fischer rats were fused with cells of the rat Y3 myeloma cell line

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.