Protein Name & Synonyms:
This antibody recognizes murine beta-glucan receptor, also known as Dectin-1.Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells.
As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens.
Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk.
Store at +4 °C.
DO NOT FREEZE
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG conjugated to R. Phycoerythrin (RPE) - liquid
Phosphate buffered saline
Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1
|1%||Bovine Serum Albumin|
Spleen cells from immunised Fischer rats were fused with cells of the rat Y3 myeloma cell line