Rat Anti-Mouse CD106

Rat Anti-Mouse CD106 (0.1 mg)

DS-MB-00255
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Antigen Information

Protein Name & Synonyms:
CD106
Target Species:
  • Mouse

Antibody Specifications

Applications:
Immunohistology - Frozen, Flow Cytometry
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Mouse

Specificity

This product recognizes murine vascular adhesion molecule 1 (VCAM-1), a cell surface glycoprotein that is also known as CD106. CD106 is expressed predominantly on endothelial cells and expression is up-regulated during inflammation. The ligand for CD106 is the alpha 4 subunit (CD49d) of the integrin VLA-4 (CD49d/CD29).
This product is reported to partially block VCAM-1 mediated functions, see Kinashi, T. & Springer, T.A. for details.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Stromal cell line PA6
Preservative:
0.09%Sodium Azide
This product
Spleen cells from immunised Lewis rats were fused with cells of the mouse P3X63Ag8.653 myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.