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Product Specifications

Size:

0.1 mg

Protein Information

Protein Name & Synonyms:

CD106

Target Species:

Mouse

Antibody Specifications

Applications:

Immunohistology - Frozen, Flow Cytometry

Concentration (lot specific):

IgG concentration 1.0 mg/ml

Species Reactivity:

Mouse

Specificity

This product recognizes murine vascular adhesion molecule 1 (VCAM-1), a cell surface glycoprotein that is also known as CD106. CD106 is expressed predominantly on endothelial cells and expression is up-regulated during inflammation. The ligand for CD106 is the alpha 4 subunit (CD49d) of the integrin VLA-4 (CD49d/CD29).
This product is reported to partially block VCAM-1 mediated functions, see Kinashi, T. & Springer, T.A. for details.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG - liquid

Formulation:

Phosphate buffered saline

Format Type:

Purified

Preparation

Immunogen:

Stromal cell line PA6

Preservative:

0.09%

Sodium Azide

This product

Spleen cells from immunised Lewis rats were fused with cells of the mouse P3X63Ag8.653 myeloma cell line.

Expiration:

12 months from the date of shipment when stored properly.