Protein Name & Synonyms:
CD11b
Applications:
Flow Cytometry
Reconstitution:
Reconstitute in 0.25 ml disilled water
Species Reactivity:
Mouse, Human
This product recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles.
This antibody immunoprecipitates a heterodimer of 165 and 95kD.
This product also exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. This product inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.
Store at +4 °C.
DO NOT FREEZE
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.
Supplied as:
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute in 0.25 ml disilled water
Immunogen:
Thioglycollate-elicted Peritoneal Macrophages (TPM)
Preservative:
0.09% | Sodium Azide |
1% | Bovine Serum Albumin |
5% | Sucrose |
This product
Spleen cells from AO rats were fused with cells of the Y3 rat myeloma cell line.