Rat Anti-Mouse CD273

Rat Anti-Mouse CD273 (0.25 mg)

$488.00
DS-MB-03789
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Antigen Information

Protein Name & Synonyms:
CD273
Target Species:
  • Mouse

Antibody Specifications

Applications:
Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Mouse

Specificity

This product recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4.

CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
B7-DC transfected RAW264.7 cells.
Preservative:
0.09%Sodium Azide
This product
Lymph node cells from immunised SD rats were fused with the cells of the P3U1 myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.