Rat Anti-Mouse CD51

Rat Anti-Mouse CD51 (0.1 mg)

DS-MB-03854
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Antigen Information

Protein Name & Synonyms:
CD51
Target Species:
  • Mouse

Antibody Specifications

Applications:
Flow Cytometry, Immunoprecipitation
Concentration:
IgG concentration 1.0mg/ml
Species Reactivity:
Mouse

Specificity

This product recognizes murine CD51, a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the intergrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61.

Heterodimers of CD51/CD61 functions as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
cultured LAK cells from Balb/c mice.
Preservative:
0.09% Sodium Azide (NaN3)
This product
Spleen cells from immunised SD rats were fused with the cells of the P3X.63Ag8.653 myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.