Rat Anti-Mouse CD8 alpha [+RPE]

Rat Anti-Mouse CD8 alpha [+RPE] (100 TESTS/1ml)

$511.00
DS-MB-03877
+

Antigen Information

Protein Name & Synonyms:
CD8 alpha
Target Species:
  • Mouse

Antibody Specifications

Applications:
Flow Cytometry
Species Reactivity:
Mouse

Specificity

This product detects mouse CD8a, the alpha chain of the CD8 antigen. CD8 is expressed on T-cells, and exists either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain.

CD8 functions as a co-receptor with the T-cell receptor and mediates efficient cell to cell interactions within the immune system. The CD8 alpha chain specifically binds to class I MHC molecules.

The antibody has been reported to block antigen presentation via MHC class I and inhibit T cell responses to IL-2. This antibody has also been used for depletion of CD8a+ cells.

Storage/Stability

Store at +4 °C. DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to R. Phycoerythrin (RPE) - liquid
Formulation:
Phosphate buffered saline

Preparation

Immunogen:
Mouse thymus or spleen.
Preservative:
0.09%Sodium Azide (NaN3)
1%Bovine Serum Albumin

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.