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Rat Anti-Mouse CD83 [+FITC]

Rat Anti-Mouse CD83 [+FITC] (0.1 mg)

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129-10172
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Antigen Information

Protein Name & Synonyms:
CD83
Target Species:
  • Mouse

Antibody Specifications

Applications:
Flow Cytometry
Concentration:
0.1mg/ml
Host Species:
Rat
Species Reactivity:
Mouse

Specificity

This product recognizes murine CD83, a 45kD type 1 glyoprotein belonging to the immunoglobulin superfamily. Originally described as a maturation marker for dendritic cells, CD83 plays a role in the regulation of antigen presentation, thymic T-cell maturation, B-cell function and peripheral T-cell activation. Activated dendritic cells and B-cells release a soluble form of CD83 that is reported to have an immunosuppressive effect, suggesting a therapeutic role for sCD83 in the regulation of immune disorders.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline

Preparation

Preservative:
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
This product
Spleen cells from immunised rats were fused with cells of the P3X63.Ag8.653 mouse myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.