Rat Anti-Mouse CD86 [+FITC]

Rat Anti-Mouse CD86 [+FITC] (0.1 mg)

$412.00
DS-MB-00910
+

Antigen Information

Protein Name & Synonyms:
CD86
Target Species:
  • Mouse

Antibody Specifications

Applications:
Flow Cytometry
Concentration:
IgG concentration 0.1 mg/ml
Species Reactivity:
Mouse

Specificity

This product recognizes mouse CD86 (B7-2), an 80kD cell surface glycoprotein which is a member of the CD28/B7 family. In mouse CD86 is expressed at high levels on peripheral blood monocytes and dendritic cells, and at low levels on resting B and T-lymphocytes. Expression of CD86, on these cell populations, can be increased upon activation.

CD86 has been identified, along with CD80 (B7-1), as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA4). CD28 and CTLA4 are two receptors that have opposing functions in T-cell stimulation. Interaction of CD86 with CD28 promotes a number of T-cell activities, whereas the binding of CD86 to CTLA4 inhibits T-cell responses.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline

Preparation

Immunogen:
Mouse B-cell line, BCL1.
Preservative:
0.09%Sodium Azide
1%Bovine Serum Albumin
This product
Spleen cells from immunised Sprague Dawley rats were fused with cells of the P3U1 myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.