Rat Anti-Mouse CD86 [+RPE]

Rat Anti-Mouse CD86 [+RPE] (25 TESTS)

$211.00
DS-MB-03887
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Antigen Information

Protein Name & Synonyms:
CD86
Target Species:
  • Mouse

Antibody Specifications

Applications:
Flow Cytometry
Reconstitution:
Reconstitute in 0.25 ml disilled water
Species Reactivity:
Mouse

Specificity

This antibody recognizes mouse CD86 (B7-2), an 80kD cell surface glycoprotein which is a member of the CD28/B7 family. In mouse CD86 is expressed at high levels on peripheral blood monocytes and dendritic cells, and at low levels on resting B and T-lymphocytes. Expression of CD86, on these cell populations, can be increased upon activation.

CD86 has been identified, along with CD80 (B7-1), as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA4). CD28 and CTLA4 are two receptors that have opposing functions in T-cell stimulation. Interaction of CD86 with CD28 promotes a number of T-cell activities, whereas the binding of CD86 to CTLA4 inhibits T-cell responses.

Storage/Stability

Store at +4 °C. DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.

Format

Supplied as:
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute in 0.25 ml disilled water

Preparation

Immunogen:
Mouse B-cell line, BCL1.
Preservative:
0.09%Sodium Azide
1%Bovine Serum Albumin
5%Sucrose
This product
Spleen cells from immunised Sprague Dawley rats were fused with cells of the P3U1 myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.