Protein Name & Synonyms:
Immunohistology - Frozen, Flow Cytometry
IgG concentration 1.0 mg/ml
This product recognizes murine CD88, a 45kD G-protein coupled cell surface receptor, which is otherwise known as C5aR. The CD88 molecule functions as a receptor for the complement component C5a, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes.
This product does not block the binding of the C5a to murine CD88.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
RBL-2H3 transfected cells expressing murine C5aR
Cells from immunised Lou/c rats were fused with cells of the X63-Ag8.653 myeloma cell line.