Rat Anti-Mouse CD98

Rat Anti-Mouse CD98 (0.1 mg)

DS-MB-03891
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Antigen Information

Protein Name & Synonyms:
CD98
Target Species:
  • Mouse

Antibody Specifications

Applications:
Flow Cytometry
Concentration:
IgG concentration 1.0mg/ml
Species Reactivity:
Mouse

Specificity

This product recognizes murine CD98 (also known as 4F2 and SLC3A2), a type II transmembrane glycoprotein which associates with members of the L-type amino transporter family to form a heterodimeric complex.

CD98 constitutes the heavy chain of the complex and is required for the surface expression and basolateral localization of the amino acid transporter complex in polarized epithelial cells. The CD98 heavy chain also interacts with beta 1 integrins and regulates their activation through the cytoplasmic domains and transmembrane regions. Studies suggest that overexpression of CD98 may contribute to cell growth and survival by regulating integrin signalling, and therefore may play an important role in tumorigenesis.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Thymic epithelial cells from mouse
Preservative:
0.09%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.