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Antigen Information
Protein Name & Synonyms:
ER-MP58
Target Species:
- Mouse
Antibody Specifications
Applications:
Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Mouse
Specificity
This antibody recognizes the murine antigen ER-MP58, which is expressed by all bone marrow-derived M-CSF- and GM-CSF-responsive myeloid blood cell precursors.
The expression of ER-MP58 remains at a high level throughout the precursor/monocyte stage and is down-regulated upon maturation into mature macrophages. The ER-MP58 antigen is used to distinguish between early myeloid-committed cells and other hematopoietic progenitors cells in the BM. The antigen has been used as a marker of murine macrophage development in the BM.
ER-MP58 is suitable for the identification of myeloid hemopoietic islands in various organs, and for embryonal studies.
The expression of ER-MP58 remains at a high level throughout the precursor/monocyte stage and is down-regulated upon maturation into mature macrophages. The ER-MP58 antigen is used to distinguish between early myeloid-committed cells and other hematopoietic progenitors cells in the BM. The antigen has been used as a marker of murine macrophage development in the BM.
ER-MP58 is suitable for the identification of myeloid hemopoietic islands in various organs, and for embryonal studies.
Storage/Stability
Store at +4 °C. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Balb/c macrophage precursor cell hybrids
Preservative:
| 0.09% | Sodium Azide |
This product
Cells from immunised rats were fused with cells of the Y3-Ag1.2.3 myeloma cell line.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
