Rat Anti-Mouse Ly6A/E

Rat Anti-Mouse Ly6A/E

$488.00
DS-MB-03919
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Antigen Information

Protein Name & Synonyms:
Ly6A/E
Target Species:
  • Mouse

Antibody Specifications

Applications:
Flow Cytometry, Immunoprecipitation, Western Blotting
Concentration:
IgG concentration 0.5mg/ml
Species Reactivity:
Mouse

Specificity

This product recognizes members of the lymphocyte activation protein-6 (Ly-6) multigene family. Specifically, it recognizes Ly-6A.2 and Ly-6E.1. Ly-6A/E is also known as stem cell antigen-1 (Sca-1). It is an 18kDa mouse glycosyl phosphatidylinositol-anchored cell surface protein of the Ly-6 gene family. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly-6.1 and Ly-6.2 allotypes. As such, it is the most common marker used for enriching adult hematopoietic stem cells. It has varied functions, it plays a role in bone formation, myoblast proliferation and differentiation and the activation and immunosuppressive function of T cells.

This antibody has been reported to induce T cell activation. RayBiotech recommends the use of This productEL for this purpose.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Borate buffered saline
Format Type:
Purified

Preparation

Immunogen:
IL-2-dependent mouse T cell line CTL-L.
Preservative:
0.09%Sodium Azide

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.