Protein Name & Synonyms:
Ly6A/E
Applications:
Flow Cytometry, Immunoprecipitation, Western Blotting
Concentration (lot specific):
IgG concentration 0.5mg/ml
Species Reactivity:
Mouse
This product recognizes members of the lymphocyte activation protein-6 (Ly-6) multigene family. Specifically, it recognizes Ly-6A.2 and Ly-6E.1. Ly-6A/E is also known as stem cell antigen-1 (Sca-1). It is an 18kDa mouse glycosyl phosphatidylinositol-anchored cell surface protein of the Ly-6 gene family. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly-6.1 and Ly-6.2 allotypes. As such, it is the most common marker used for enriching adult hematopoietic stem cells. It has varied functions, it plays a role in bone formation, myoblast proliferation and differentiation and the activation and immunosuppressive function of T cells.
This antibody has been reported to induce T cell activation. RayBiotech recommends the use of This productEL for this purpose.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG - liquid
Formulation:
Borate buffered saline
Immunogen:
IL-2-dependent mouse T cell line CTL-L.
Expiration:
12 months from the date of shipment when stored properly.