Rat Anti-Mouse MHC Class II I-Ak,s,r

Rat Anti-Mouse MHC Class II I-Ak,s,r

$571.00
DS-MB-03947
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Antigen Information

Protein Name & Synonyms:
MHC Class II I-Ak,s,r
Target Species:
  • Mouse

Antibody Specifications

Applications:
Immunohistology - Frozen, Flow Cytometry
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Mouse

Specificity

The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the H-2 region.

This product recognizes a polymorphic determinant of the mouse H-2I-A MHC class II antigen, reacting with haplotypes k, s and r. Mouse strains with the haplotypes b, d, q and f are not recognized by this antibody.

Mouse MHC class II antigens are expressed by dendritic cells, B-cells and macrophages. In thymus tissues, This product stains cortical and medullary stromal cells.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Isolated C3H thymic stromal cells
Preservative:
0.09%Sodium Azide
This product
Cells from immunised rats were fused with cells of the mouse P3-X63-Ag8.56 myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.