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Antigen Information
Protein Name & Synonyms:
NKG2A/C/E
Target Species:
- Mouse
Antibody Specifications
Applications:
Flow Cytometry, Functional Assays
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Mouse
Specificity
This product recognizes murine NKG2A, NKG2C and NKG2E, which are isoforms of the NKG2 lectin-like family. In mice, NKG2 subunits associate with CD94 to form heterodimers at the surface of natural killer (NK) cells.
The CD94/NKG2 heterodimer is the receptor for a non-classical MHC class I ligand, which is Qa-1 in the mouse.
This product is reported to block ligand binding to the receptor, see Vance, R. E. et al. for details.
The CD94/NKG2 heterodimer is the receptor for a non-classical MHC class I ligand, which is Qa-1 in the mouse.
This product is reported to block ligand binding to the receptor, see Vance, R. E. et al. for details.
Storage/Stability
Store at -20 °C only.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Quality Control (Contaminants):
<0.01 Eu/ug
Format Type:
Low Endotoxin
Preparation
Immunogen:
CHO transfected cells expressing the B6 allele of NKG2A.
Preservative:
None present
This product
Spleen cells from immunised Lewis rats were fused with cells of the mouse P3X63-Ag8.653 myeloma cell line.
No posts found
Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
