Publications by RayBiotech Scientists

Weisheng, B., Nezhat, C. H., Huang, G. F., Mao, Y. Q., Sidell, N., & Huang, R. P. (2019). Discovering endometriosis biomarkers with multiplex cytokine arrays. Clinical proteomics, 16(1), 28.

Huang, W., Wu, J., Mao, Y., Zhu, S., Huang, G. F., Petritis, B., & Huang, R. P. (2019). Developing a periodontal disease antibody array for the prediction of severe periodontal disease using machine learning classifiers. Journal of Periodontology.

Whittaker, K., Burgess, R., Jones, V., Yang, Y., Zhou, W., Luo, S., ... & Huang, R. P. (2019). Quantitative proteomic analyses in blood: A window to human health and disease.Journal of leukocyte biology, 106(3), 759-775.

Yang, Q., Chen, Q., Zhang, M., Cai, Y., Yang, F., Zhang, J., ... & Zhang, H. (2020). Identification of eight-protein biosignature for diagnosis of tuberculosis. Thorax.

Tan, F., Chen, X., Zhang, H., Yuan, J., Sun, C., Xu, F., ... & Wang, C. (2020). Differences in serum proteins in traditional Chinese medicine constitutional population: Analysis and verification. Journal of Leukocyte Biology.

Kuang, Z., Huang, R., Yang, Z., Lv, Z., Chen, X., Xu, F., ... & Huang, R. P. (2018). Quantitative screening of serum protein biomarkers by reverse phase protein arrays. Oncotarget, 9(66), 32624.

Huang, W., Luo, S., Burgess, R., Yi, Y. H., Huang, G., & Huang, R. P. (2018). New insights into the tumor microenvironment utilizing protein array technology. International journal of molecular sciences, 19(2), 559.

Huang, W., Whittaker, K., Zhang, H., Wu, J., Zhu, S. W., & Huang, R. P. (2018). Integration of Antibody Array Technology into Drug Discovery and Development. Assay and drug development technologies, 16(2), 74-95.

Xi, Y., Zhang, Y., Fang, J., Whittaker, K., Luo, S., & Huang, R. P. (2017). Prokaryotic Expression of Hepatitis C Virus-NS3 Protein and Preparation of a Monoclonal Antibody. Monoclonal antibodies in immunodiagnosis and immunotherapy, 36(6), 251-258.

Schwartzbaum, J., Wang, M., Root, E., Pietrzak, M., Rempala, G. A., Huang, R. P., ... & Grimsrud, T. K. (2017). A nested case-control study of 277 prediagnostic serum cytokines and glioma. PloS one, 12(6), e0178705.

Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hoffree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T. "Network-Driven Plasma Proteomics Expose Molecular Changes in the Alzheimer’s Brain." Molecular Neurodegeneration 11 (2016): 31. PMC. Web. 4 May 2016.

Zhang Y, Xi Y, Fang J, Luo S, Wilson JJ, Huang RP. "Identification and characterization of monoclonal antibodies against GP73 for use as a potential biomarker in liver cancer screening and diagnosis." J Immunoassay Immunochem. 2016;37(4):390-406. doi: 10.1080/15321819.2016.1154866.

Judith Schwartzbaum*, Michal Seweryn, Christopher Holloman, Randall Harris, Samuel K. Handelman, Grzegorz A. Rempala, Ruo-Pan Huang, Brett Burkholder, Adam Brandemihl, Henrik Kallberg, Tom Borge Johannesen, Anders Ahlbom, Maria Feychting, Tom K. Grimsrud. "Association between Prediagnostic Allergy Related Serum Cytokines and Glioma." PLoS ONE 10(9):e0137503. doi:10.1371/journal.pone.0137503

Yun Xi*, Yuming Zhang*, Jianmin Fang, Jarad J. Wilson, Shuhong Luo, and Ruo-Pan Huang(2015) Development of Monoclonal Antibodies and Characterization of an ELISA Platform Against Kallikrein-related Peptidase 6 as a Tumor Biomarker. MONOCLONAL ANTIBODIES IN IMMUNODIAGNOSIS AND IMMUNOTHERAPY Volume 34, Number 5, 2015

Weidong Jiang, Ruochun Huang, Chaohui Duan, Liwu Fu, Yun Xi, Yuebo, Yang, Wei-Min Yang, Dongzi Yang, Dong-Hua Yang, Ruo-Pan Huang*, (2013) Identification of five serum protein markers for detection of ovarian cancer by antibody arrays. Plos One. Volume 8 | Issue 10 | e76795.

Weidong Jiang, Ying Qing Mao, Ruochun Huang, QianShi, Jean Yang, Rani Huang, Kai Yang, Ruo-Pan Huang(2013) Profiling protein expression by antibody array analysis with use of dried blood spot samples on filter paper. Journal of immunological method. 403 (2014) 79–86.
*One of the top downloaded articles from database ScienceDirect and recommended by ScienceDirect to researchers.

Zhou,Q., Mao, Y.Q., Jiang, W.D., Chen,Y.R., Huang, R.Y., Zhou, X.B., Wang, Y.F., Shi, Z., Wang, Z.S., and Huang,R.P.(2012). Development of IGF Signaling Antibody Arrays for the Identification of Hepatocellular Carcinoma Biomarkers. PLoS One. 7.

Shi,Z., Yang,W.M., Chen, L.P., Yang, D.H., Zhou,Q., Zhu, J., Chen,J.J., Huang,R.C., Chen,Z.S., and Huang,R.P. (2012). Enhanced chemosensitization in multidrug-resistant human breast cancer cells by inhibition of IL-6 and IL-8 production. Breast Cancer Res Treat. 2012.135,737-747.

Browne AS, Yu,J., Huang,R.P., Francisco AM, Sidell N, and Taylor RN.(2012). Proteomic identification of neurotrophins in the eutopic endometrium of women with endometriosis. Fertil Steril. 98,713-719.

Huang,R.C., Jiang W.D., Yang, J., Mao,Y.Q., Zhang,Y., Yang, W., Yang, D., Burkholder B, Huang,R.F., and Huang, R.P. (2010). A biotin label-based antibody array for high-content profiling of protein expression. Cancer Genomics Proteomics. 7,129-141.

Sarah L. Tressel, Ruo-Pan Huang, Nicholas Tomsen, Hanjoong Jo. (2007). Laminar shear inhibits tubule formation and migration of endothelial cells by an angiopoietin-2-dependent mechanism. Arterioscler Thromb Vasc Biol. 2007 Oct;27(10):2150-6. Epub 2007 Aug 2.

Ruochun Huang, Shiyong Li, Weimin Yang, Lipai Chen, Chen Yao and Ruo-Pan Huang. (2006) Early growth response-1 suppresses human fibrosarcoma cell invasion and angiogeneis. Cancer Genomics and Proteomics. 3:71-82.

Ying Lin, Shengmin Huang, Ruo-Pan Huang. (2005) Angiogenic effect of interleukin-8 in breast cancer and its association with estrogen receptor. Zhonghua Yi Xue Za Zhi. 1;85(20):1419-23.

Ruochun Huang, Ying Lin, Lisa Flowers, Henry Lisoukov, Qian Wang, Qian Shi, Ira R. Horowitz, Sampath Parthasarathy and Ruo-Pan Huang. (2004) Molecular profiling of cytokine levels in human ovarian cancer patients. Cancer Genomics and Proteomics. 1: 23-32.

Ruochun Huang, Ying Lin, Qian Shi, Lisa Flowers, Sumathi Ramachandran, Ira Horowitz, Sampath Parthasarathy and R.-P. Huang. (2004) Profiling of angiogenesis factors in gynecological malignancies by Enhanced protein profiling arrays. Clinical Cancer Res. 10:598-609.

Ying Lin, Ruochun Huang, Lipai Chen, Siyong Li, Qian Shi, Craig Jordan and Ruo-Pan Huang. (2004) Identification of IL-8 as estrogen receptor-regulated factor involved in breast cancer invasion and angiogenesis by protein arrays. Int. J. Cancer. 109: 507-515.

Y. Lin, Ruochun Huang, Li-Pai Chen, Henry Lisoukov, Zhen-Hai Lu, Shiyong Li, Cheng C. Wang and R.-P. Huang. (2003) Profiling of cytokine expression by biotin-labeled-based protein arrays. Proteomics. 3: 1750-1757.

T. Wanichkul, S. W. Han, R.-P. Huang and N. Sidell. (2003) Cytokine regulation by peroxisome proliferator-activated receptor gamma in human endometrial cells. Fertility and Sterility. 79: 763-769.

Ying Lin, Ruochun Huang, Xuan Cao, Shen-Ming Wang , Qing Shi and Ruo-Pan Huang. (2003). Detection of multiple cytokines by protein arrays from cell lysate and tissue lysate. Clin Chem Lab Med. 41:139-145.

Y. Lin, R. Huang, N. Santanam, Y.-G. Liu, S. Parthasarathy and R.-P. Huang. (2002). Profiling of human cytokines in healthy individuals with vitamin E supplementation by antibody arrays. Cancer letter. 187: 17-24.

C. C. Wang, R.-P. Huang, H. Lisoukov, M. Sommer, R. Huang, Y. Lin and J. Burke. (2002) Array-based multiplexed screening and quantitation of human cytokines and chemokines. J. Proteome Res. 1:337-343.

R. Huang, Y. Lin, C. C. Wang, J. Gano, B. Lin, Q. Shi, A. Boynton, J. Burke and R.-P. Huang. (2002) Connexin suppresses human glioblastoma cell growth by down-regulation of monocyte chemotactic protein 1, as discovered using protein array technology. Cancer Res. 62 : 2806-2812.

R.-P. Huang, R. Huang, Y. Fan and Y. Lin. (2001). A novel method for high-throughput protein profiling from conditioned media and patient’s sera. Ana. Biochem. 294(1):55-62.

R.-P. Huang.(2001) Detection of multiple proteins in an antibody-based protein microarray system. J. Immunological Method. 255:1-13.
One of the top downloaded articles from database ScienceDirect and recommended by ScienceDirect to researchers.

R.-P. Huang. (2001). Simultaneous detection of multiple proteins with an array-based enzyme-linked immunosorbant assay (ELISA) and enhanced chemiluminescence (ECL). Clin. Chem. Lab. Med. 39:209-214.