Recombinant Human GALECTIN-1
Purified recombinant galectin-1 expressed in <em>E.coli</em>
Purified recombinant protein - lyophilized
10mM Sodium phosphate pH7.5
Total protein concentration ~0.1 mg/ml after reconstitution
>98% by SDS PAGE/HPLC analysis
< 1 EU/ug
ELISA (0.2-0.4ng/well), Functional Assays, Western Blotting (1.5-3.0ng/lane)
Protein Name & Synonyms:
Molecular Weight (kDa):
14.5kD (134 amino acid residues)
Human galectin-1 (Gal-1) is a member of the galectin family of beta-galactoside-binding proteins, which exhibits both intracellular and extracellular functions, and is differentially expressed by a wide range of normal and neoplastic tissues.
Galectin-1 has been implicated in several major cellular functions including proliferation, motility, haematopoietic cell differentiation, apoptosis promotion and immunoregulatory effects. The expression of Gal-1 by neuronal and glial cells correlates with neuroregeneration following injury, and studies have shown the importance of Gal-1 to primary sensory neurons and synaptic connections in the spinal cord, during embryonic development.
Prior to reconstitution store at +4°C.
After reconstitution store at -20°C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution.