Sheep Anti-Guinea Pig Calretinin

Sheep Anti-Guinea Pig Calretinin

129-10333
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Antigen Information

Protein Name & Synonyms:
Calretinin
Target Species:
  • Guinea Pig

Antibody Specifications

Applications:
Immunohistology - Frozen, Western Blotting
Host Species:
Sheep
Species Reactivity:
Guinea Pig, Rat

This product detects a band of approximately 29kDa in rat cerebellum.

Specificity

This product recognizes calretinin, a 29kDa calcium binding protein found mostly in the central nervous system and retina. It is a cytoplasmic protein involved in the regulation of calcium concentration, which is important in the regulation of a large variety of neuronal functions, including neurotransmitter release, ionic channel permeability, enzyme activity, and gene transcription. Mice deficient in calretinin show impairment in motor coordination.

Calretinin has also been shown as a sensitive and specific marker for mast cells.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
TRIS buffered saline
Format Type:
Purified

Preparation

Antisera to Calretinin were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG was prepared from whole serum by Protein A chromatography.

Immunogen:
Purified guinea pig calretinin
Preservative:
0.09% Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.