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Antigen Information

Protein Name & Synonyms:

Calretinin

Target Species:

Guinea Pig

Antibody Specifications

Applications:

Immunohistology - Frozen, Western Blotting

Host Species:

Sheep

Species Reactivity:

Guinea Pig, Rat

This product detects a band of approximately 29kDa in rat cerebellum.

Specificity

This product recognizes calretinin, a 29kDa calcium binding protein found mostly in the central nervous system and retina. It is a cytoplasmic protein involved in the regulation of calcium concentration, which is important in the regulation of a large variety of neuronal functions, including neurotransmitter release, ionic channel permeability, enzyme activity, and gene transcription. Mice deficient in calretinin show impairment in motor coordination.

Calretinin has also been shown as a sensitive and specific marker for mast cells.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG - liquid

Formulation:

TRIS buffered saline

Format Type:

Purified

Preparation

Antisera to Calretinin were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG was prepared from whole serum by Protein A chromatography.

Immunogen:

Purified guinea pig calretinin

Preservative: