Sheep Anti-Human Indoleamine Dioxygenase

Sheep Anti-Human Indoleamine Dioxygenase

$761.00
DS-PB-01146
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Antigen Information

Protein Name & Synonyms:
Indoleamine Dioxygenase
Target Species:
  • Human

Antibody Specifications

Applications:
Immunohistology - Paraffin, Western Blotting
Concentration:
Total protein concentration 27.1 mg/ml
Preparation:
Antisera to human indoleamine dioxygenase (IDO) were raised by repeated immunisation of sheep with highly purified antigen. Ig fraction prepared by ammonium sulfate precipitation.
Species Reactivity:
Human, Marmoset, Rhesus Monkey

Specificity

This product recognizes human indoleamine 2,3-dioxygenase (IDO), an enzyme that is responsible for converting tryptophan to kynurenines. IDO is expressed by a wide variety of tissues and IDO can be upregulated by interferon gamma. IDO modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. Reports suggest that IDO is involved in the suppression of the immune response to tumours and blocking the IDO pathway may be a potential target for immunotherapy.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Ig Fraction - liquid
Formulation:
Phosphate buffered saline
Format Type:
Ig Fraction

Preparation

Antisera to human indoleamine dioxygenase (IDO) were raised by repeated immunisation of sheep with highly purified antigen. Ig fraction prepared by ammonium sulfate precipitation.

Immunogen:
Recombinant human indoleamine 2,3-dioxygenase.
Preservative:
0.09%Sodium Azide

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.