Sheep Anti-Human Lactoferrin [+FITC]

Sheep Anti-Human Lactoferrin [+FITC]

DS-PB-03018
+

Antigen Information

Protein Name & Synonyms:
Lactoferrin
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA
Concentration:
IgG concentration 1.0 mg/ml
Preparation:
Antisera to human lactoferrin were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography.
Species Reactivity:
Human, Dog

Specificity

This product recognizes human lactoferrin (LTF), an 80kDa non-hem, iron-binding globular glycoprotein and member of the transferrin family present in milk and mucosal secretions, and also released from neutrophil granules during inflammation.

LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline

Preparation

Antisera to human lactoferrin were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography.

Immunogen:
Lactoferrin purified from milk
Preservative:
0.09%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.