Sheep Anti-Human Lactoferrin [+HRP]

Sheep Anti-Human Lactoferrin [+HRP]

DS-PB-03019
+

Antigen Information

Protein Name & Synonyms:
Lactoferrin
Target Species:
  • Human

Antibody Specifications

Applications:
Immunohistology - Frozen, ELISA (dilution: , 1/50), Immunohistology - Paraffin
Concentration:
IgG concentration 1.0mg/ml
Preparation:
Antisera to human lactoferrin were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography.
Species Reactivity:
Human, Dog

Specificity

This product recognizes human lactoferrin (LTF), an 80kDa non-hem, iron-binding globular glycoprotein and member of the transferrin family present in milk and mucosal secretions, and also released from neutrophil granules during inflammation.

LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to Horseradish Peroxidase (HRP) - liquid
Formulation:
Phosphate buffered saline

Preparation

Antisera to human lactoferrin were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography.

Immunogen:
Lactoferrin purified from milk.
Preservative:
0.01%Thiomersal

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.