Sheep Anti-Human Plasminogen [+HRP]

Sheep Anti-Human Plasminogen [+HRP]

$412.00
DS-PB-03022
+

Antigen Information

Protein Name & Synonyms:
Plasminogen
Target Species:
  • Human

Antibody Specifications

Applications:
Immunohistology - Frozen, ELISA
Concentration:
IgG concentration 1.0mg/ml
Preparation:
Antisera to human plasminogen were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography.
Species Reactivity:
Human, Bovine, Cat, Dog, Guinea Pig, Rat

Specificity

This product recognizes human plasminogen, a 92kDa single-chain glycoprotein and inactive precursor (zymogen) of plasmin, secreted by the liver and present in the blood and majority of extravascular body fluids.

Plasminogen is the central component in the fibrinolytic system, and is converted into active plasmin through cleavage by the endogenous activators urokinase (u-PA) and tissue plasminogen activator (t-PA), in the presence of fibrin. The level of plasminogen is maintained in the plasma at around 200mg/L, with an increase being associated with hypothyroidism, obesity and pregnancy, and deficiencies with many disorders including thrombosis, liver disease, sepsis and hyperthyroidism.

This product may cross react with plasminogen from other species.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to Horseradish Peroxidase (HRP) - liquid
Formulation:
Phosphate buffered saline

Preparation

Antisera to human plasminogen were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography.

Immunogen:
Native, highly purified.
Preservative:
0.01%Thiomersal

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.