Protein Name & Synonyms:
Transferrin
Applications:
Immunofluorescence
Concentration (lot specific):
IgG concentration 1.0mg/ml
Preparation:
Antisera to human transferrin were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography on protein G
Species Reactivity:
Human
This product recognizes human transferrin, an approximately 80kDa blood plasma glycoprotein synthesised by the liver, which contains two specific high affinity iron (Fe3+) binding sites and is responsible for the transport and supply of an exchangeable pool of iron, through binding to cell surface transferrin receptors.
Transferrin is the primary blood iron transport protein and under normal conditions, approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and hemochromatosis.
This product shows minimal cross reactivity with related serum proteins.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Antisera to human transferrin were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography on protein G
Immunogen:
Pure human transferrin prepared from pooled normal human serum.
Expiration:
12 months from the date of shipment when stored properly.