Sheep Anti-Rat Tyrosine Hydrolase

Sheep Anti-Rat Tyrosine Hydrolase

$667.00
129-10665
+

Antigen Information

Protein Name & Synonyms:
Tyrosine Hydrolase
Target Species:
  • Rat

Antibody Specifications

Applications:
Immunohistology - Frozen, Immunofluorescence, Western Blotting
Host Species:
Sheep
Species Reactivity:
Rat, Mammals

This product detects a band of approximately 60kDa in rat caudate cell lysates.

Specificity

This product is specific for Tyrosine hydroxylase (TH).

Tyrosine hydroxylase catalyses the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain.

Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
10mM HEPES pH7.5, 150mM NaCl
Format Type:
Purified

Preparation

Antisera to tyrosine hydroxylase were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by immunoaffinity chromatography.

Immunogen:
Rat Tyrosine hydroxylase purified from pheochromocytoma.
Preservative:
0.09% Sodium Azide (NaN3)
0.01% Bovine Serum Albumin
50% Glycerol

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.