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INTERACTIVE PATHWAY MAPS
Akt Signaling Pathway
The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of stimuli and controls fundamental cellular processes such as apoptosis, metabolism, proliferation, protein synthesis, growth, and survival. Dysregulation of this pathway is…
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JAK/STAT Signaling Pathway
The JAK/STAT pathway is a principal signaling mechanism for many cytokines and growth factors and provides a direct mechanism to translate extracellular signals into transcriptional responses. Activation of this pathway stimulates cell proliferation, differentiation…
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Notch Signaling Pathway
The Notch signaling pathway is a highly conserved system present in many multicellular organisms. Mammals are known to express four different notch receptors, called Notch1, Notch2, Notch3, and Notch4. Notch signaling is crucial in a wide array of developmental processes…
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NF-KappaB Signaling Pathway
The nuclear factor-κB (NF-κB)/Rel family members function as dimeric transcription factors that play important roles in regulating the expression of cytokines, growth factors, and inhibitors of apoptosis. Two signaling pathways lead to the activation of NF-κB, known as the…
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AMPK Signaling Pathway
AMP-activated protein kinase (AMPK) is a central regulator of cellular energy homeostasis, playing critical roles in regulating growth and reprogramming metabolism as well as in cellular processes including autophagy and cell polarity. The kinase is activated in response to…
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Hedgehog Signaling Pathway
Hedgehog is an evolutionarily conserved pathway which initiates a range of cellular responses including proliferation, differentiation, survival and cell fate decisions. The human homolog, Sonic hedgehog (Shh) is a diffusible morphogen which directs development, maintenance…
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MAPK Signaling Pathway
The mitogen-activated protein kinase (MAPK) signaling pathway is activated by a number of extra and intracellular stimuli including cytokines, growth factors, and hormones as well as stressors such as oxidative and ER stress. This pathway plays a key role in the regulation…
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TGF-beta Signaling Pathway
Transforming growth factor-β (TGF-β) signaling plays a key role tissue homeostasis, which is accomplished through dynamic regulation of many cellular processes, including cell growth, migration, differentiation, epithelial-mesenchymal transition, and extracellular matrix…
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FEATURED PRODUCTS & SERVICES
ELISA
Over 2,000 ISO-Certified ELISAs available for a variety of sample types. Our most referenced ELISAs:
- Mouse TNF-alpha
- Human VEGF-A
- Rat TNF-alpha
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C-Series: Membrane-Based Antibody Arrays
Multiplex western blot arrays to detect multiple proteins simultaneously. Our most referenced C-series Arrays:
- Mouse Cytokine C3
- Human Cytokine C6
- Rat Cytokine C1
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Ultrasensitive Biomarker Testing Service
Single molecule array testing is a powerful new technique that is orders of magnitude more sensitive than standard sandwich based immunoassay techniques. Our Ultrasensitive Simoa Testing Services can achieve sensitivity as low as femtogram levels.
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Why Run Your Own Westerns?
Leave the burden of validating antibodies and optimizing conditions to us. RayBiotech’s Auto-Western Service marries our state-of-the-art capillary immunoblotting system with our vast pre-validated antibody library, for as little as $30 per sample!
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POSTS, PAPERS, & PUBLICATIONS
RayBio® Arrays Acknowledged in Recent Nature Biomedical Engineering publication
See how RayBiotech’s arrays were used by a group at Mass Gen to uncover cytokine profiles of swarming Neutrophils in a cool new ex vivo swarming model.
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RayBio G4000 Arrays Used to Identify Biomarkers of Glioma
RayBiotech is proud to see not only our G4000 cytokine array used in a publication, but also our Founder Dr. Huang. In a recent retrospective evaluation of glioma patients’ blood, this group identified some pre-diagnostic biomarkers in the serum of future glioma patients.
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RayBio® Cytokine Arrays Used in JEM Publication
RayBiotech C-Series Membrane-based Antibody Arrays were used in a recent Journal of Experimental Medicine publication titled “MD-2 is required for disulfide HMGB1–dependent TLR4 signaling.”
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