Autoimmunity & Inflammation
Understanding the Role of Inflammatory Proteins in Disease
Inflammation plays a crucial role in the pathogenesis of many diseases, including cancer, cardiovascular disease, and autoimmune disorders. Inflammatory proteins/cytokines regulate immune and inflammatory responses and are key players in the development and progression of these diseases.
Autoimmune diseases (AIDs) arise when the immune system mistakenly targets the body’s own tissues, leading to chronic inflammation, tissue damage, and a wide spectrum of clinical disorders such as lupus, rheumatoid arthritis, and multiple sclerosis. Inflammation is not merely a symptom of these conditions—it is a central pathological process driven by autoreactive immune cells and autoantibodies. The ability to identify and monitor these autoimmune responses is crucial for understanding disease mechanisms, improving diagnostics, and developing targeted therapies.
To support researchers investigating these complex immunological processes, RayBiotech offers powerful tools for profiling autoantibody and cytokine signatures associated with AIDs. Our Human Autoimmune Disease Biomarker Screening Array enables high-throughput detection of multiple inflammatory and autoimmune biomarkers in a single experiment, while the Human Autoimmune Disease IgG Autoantibody Array allows for sensitive identification of IgG autoantibodies linked to various autoimmune conditions. These innovative arrays provide comprehensive insights into immune dysregulation and disease progression—advancing both basic and pre-clinical autoimmune research.
In addition, RayBiotech has a large catalog of inflammation research products, including ELISA kits, antibody arrays, and flow cytometry reagents for immune response research. Full testing services are available for all RayBiotech products, including flow cytometry.
Typical data using human serum on the RayBio® Autoimmune Disease IgG Autoantibody Detection Array. Protein arrays were incubated with sera healthy donors or patients with various autoimmune diseases. Two different individuals are represented for each condition. Yellow boxes indicate control spots (biotin-labeled BSA).