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Anti-Acetyl-Histone H2B-K12 Antibody

Catalog #: 144-63840

Acetyl-Histone H2B-K12 pAb

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse, Rat
Host SpeciesRabbit
Accession Number
Q16778
Gene Id
8349
Gene Symbols
H2B K12ac
Protein Name / Synonyms
HIST2H2BE, GL105, H2B, H2B.1, H2BFQ, H2BGL105, H2BQ, histone H2B type 2-E
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting, IHC, IF
Shipping TypeBlue ice
Storage-20°C

Description

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity.

Dilutions

WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200

Format

Calculated MW
13kDa
Observed MW
14kDa

Immunogen

A synthetic acetylated peptide around K12 of human Histone H2B (NP_003519.1).

Modification

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:
12 months from the date of shipment when stored properly.