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Anti-Acetyl-Histone H3-K18 Antibody
Catalog #: 144-66342
Acetyl-Histone H3-K18 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P68431 |
| Gene Id | 8356 |
| Gene Symbols | H3K18ac |
| Protein Name / Synonyms | HIST1H3J, H3/j, H3FJ, histone H3.1 |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC, IF, IP, ChIP, ChIPseq |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
Dilutions
WB 1:1000 - 1:3000; IHC 1:200 - 1:500; IF 1:500 - 1:1000; IP 1:200 - 1:500; CHIP 1:50 - 1:100; CHIPseq 1:50 - 1:100
Format
Calculated MW
15kDa
Observed MW
16kDa
Immunogen
A synthetic acetylated peptide corresponding to residues surrounding K18 of human H3
Modification
Acetyl K18
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.