Anti-Acetyl-Histone H3-K9/K14/K18/K23/K27 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	P68431
Gene Id	8350
Gene Symbols	H3K9ac,H3K14ac,H3K18ac,H3K23ac,H3K27ac
Protein Name / Synonyms	HIST3H3, H3.4, H3/g, H3FT, H3t, histone H3.1t
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting, IHC, IF
Research Area	Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Dilutions

IHC 1:50 - 1:200; IF 1:50 - 1:200

Format

Calculated MW

Observed MW

Immunogen

A synthetic peptide of human Acetyl-Histone H3-K9/K14/K18/K23/K27.

Modification

Storage

Store at -20°. Avoid freeze / thaw cycles.

Expiration:

12 months from the date of shipment when stored properly.

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