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Anti-Acetyl-Histone H4-K8 Antibody
Catalog #: 144-66343
Acetyl-Histone H4-K8 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P62805 |
| Gene Id | 8370 |
| Gene Symbols | H4K8ac |
| Protein Name / Synonyms | HIST2H4A, FO108, H4, H4/n, H4F2, H4FN, HIST2H4, histone H4 |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC, IF, IP, ChIP, ChIPseq |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
Dilutions
WB 1:1000 - 1:3000; IHC 1:200 - 1:500; IF 1:500 - 1:1000; IP 1:200 - 1:500; CHIP 1:20 - 1:50; CHIPseq 1:20 - 1:50
Format
Calculated MW
11kDa
Observed MW
11kDa
Immunogen
A synthetic peptide of human Acetyl-Histone H4-K8
Modification
Acetyl K8
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.