Anti-ACTA1 Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P68133
Gene Id	58
Gene Symbols	ACTA1
Protein Name / Synonyms	ACTA1
Clonality	Monoclonal
Preparation	This ACTA1 monoclonal antibody is generated from mouse immunized with ACTA1 recombinant protein.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine, Chicken, Pig, Rabbit

Other Names

ACTA1; ACTA; Actin, alpha skeletal muscle; Alpha-actin-1

NCBI Accession #

NP_001091.1

Other Accession #

P68136; P68135; P68137; P68134; P68139; P68138; NP_001091.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

42051

Recommended Dilutions

WB: 1:100-500; IHC: 1:10-50; FC: 1:10-50

	ACTA1 Antibody(Cat# 102-10202) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ACTA1 antibody detected the ACTA1 protein (arrow).
	ACTA1 Antibody (Cat# 102-10202)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ACTA1 Antibody for immunohistochemistry. Clinical relevance has not been evaluated.
	ACTA1 Antibody (Cat# 102-10202)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ACTA1 Antibody for immunohistochemistry. Clinical relevance has not been evaluated.
	ACTA1 Antibody (Cat# 102-10202) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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