Anti-ACTL6A (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O96019
Gene Id	86
Gene Symbols	ACTL6A
Protein Name / Synonyms	ACTL6A (N-term)
Clonality	Polyclonal
Preparation	This ACTL6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-30 amino acids from the N-terminal region of human ACTL6A.
Concentration (lot specific)	0.400 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.

Specificity

Predicted Reactivity

Mouse, Monkey

Other Names

ACTL6A; BAF53; BAF53A; INO80K; Actin-like protein 6A; 53 kDa BRG1-associated factor A; Actin-related protein Baf53a; ArpNbeta; BRG1-associated factor 53A; INO80 complex subunit K

NCBI Accession #

NP_004292.1;NP_817126.1;NP_829888.1

Other Accession #

Q9Z2N8; Q4R333; NP_817126.1; NP_004292.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

47461

Recommended Dilutions

WB: 1:1000

ACTL6A Antibody (N-term) (Cat# 102-13229) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ACTL6A antibody detected the ACTL6A protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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