Anti-ADRA1B (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P35368
Gene Id	147
Gene Symbols	ADRA1B
Protein Name / Synonyms	ADRA1B (C-term)
Clonality	Polyclonal
Preparation	This ADRA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-409 amino acids from the C-terminal region of human ADRA1B.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

Specificity

Predicted Reactivity

Mouse, Rat

Other Names

ADRA1B; Alpha-1B adrenergic receptor; Alpha-1B adrenoreceptor

NCBI Accession #

NP_000670.1

Other Accession #

P15823; P97717; NP_000670.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

56836

Recommended Dilutions

WB: 1:1000

ADRA1B Antibody (C-term) (Cat# 102-14483) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ADRA1B antibody detected the ADRA1B protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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