Anti-AK1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P00568
Gene Id	203
Gene Symbols	AK1
Protein Name / Synonyms	AK1 (N-term)
Clonality	Polyclonal
Preparation	This AK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human AK1.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.

Specificity

Other Names

AK1; Adenylate kinase isoenzyme 1; ATP-AMP transphosphorylase 1; Myokinase

NCBI Accession #

NP_000467.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

21635

Recommended Dilutions

WB: 1:1000

	Western blot analysis of anti-AK1 Pab (Cat# 102-17841) in Jurkat cell line lysate (35ug/lane). AK1(arrow) was detected using the purified Pab.
	Western blot analysis of AK1 (arrow) using rabbit polyclonal AK1 Antibody (S45) (Cat# 102-17841). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the AK1 gene.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products