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Anti-ALDH2 (Center) Antibody
Catalog #: 102-12433
Rabbit Anti-Human ALDH2 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P05091 |
| Gene Id | 217 |
| Gene Symbols | ALDH2 |
| Protein Name / Synonyms | ALDH2 (Center) |
| Clonality | Polyclonal |
| Preparation | This ALDH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 amino acids from the Central region of human ALDH2. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
ALDH2; ALDM; Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDHI
NCBI Accession #
NP_000681.2;NP_001191818.1
Other Accession #
P11884; P47738
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
56381
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | ALDH2 Antibody (Center) (Cat# 102-12433) western blot analysis in A549 cell line,mouse liver and lung,rat liver lysates (35ug/lane).This demonstrates the ALDH2 antibody detected the ALDH2 protein (arrow). |
 | Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH2 antibody (Center) (Cat# 102-12433), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.